Table 2 Recommendations for diagnostic LP in thrombocytopenia (see also cross-sectional guideline of the Bundesärztekammer on therapy with blood components and plasma derivatives (https://www.bundesaerztekammer.de/fileadmin/user_upload/downloads/pdf-Ordner/WB/QLL_Haemotherapie-englisch.pdf))
From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)
| Thrombocyte count /μL | Procedure for a planned LP |
|---|---|
| > 50,000 | If there are no other contraindications. |
| 10,000–50,000 | Relative contraindication. An increased risk of bleeding is to be expected. Substitute thrombocytes if necessary. |
| < 10,000 | Absolute contraindication. Thrombocyte substitution before LP mandatory. |