Table 17 Expected patterns of the CSF biomarkers in different neurodegenerative disorders
From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)
| Ab42 or Ab42/40 | Tau | pTau | |
|---|---|---|---|
| Alzheimer’s disease | ↓ | ↑ | ↑ |
| Vascular Dementia | ↔ | (↑) | (↑) |
| bvFTD | ↔ | (↑) | (↑) |
| nf-avPPA | ↔ | (↑) | (↑) |
| svPPA | ↔ | ↔ | ↔ |
| lvPPA | ↓ | ↑ | ↑ |
| CBD | (↔) | (↑) | (↑) |
| DLB | (↔) | (↑) | (↑) |